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Archive for October, 2013

XReminder: A Reminder app with quick gesture controls | AppSaga

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XReminder – Quick & Powerful Reminder (4.5 stars with 35 Ratings) 
iPhone App

$1.99

Free Offer Ended. This app was free on October 29, 2013, but the offer has expired. Follow us on Twitter or Subscribe by email or RSS feed to get daily App Gone Free notifications so you won’t miss it next time. The following impression was made during the promotional period.

 

Looking for an easy-to-use reminder app with gesture controls?

At first glance, this may seem just like another countdown app, although that’s partially true, this app is more of a reminder app with quick and easy gesture controls. Simply drag down on the screen to create an item. Enter a title, time, any recurring options, and you are done. Swipe left or right to edit or delete it. If you are looking for a quick and easy app to set your reminders, try out XReminders.

App Screenshots

– See more at: http://appsaga.com/xreminder-a-reminder-app-with-quick-gesture-controls/#sthash.0vWnPyBM.dpuf

via XReminder: A Reminder app with quick gesture controls | AppSaga.

Bucatini with Butter-Roasted Tomato Sauce

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INGREDIENTS

1 28-oz. can whole peeled tomatoes

8 garlic cloves, peeled, crushed

2 anchovy fillets packed in oil

¼ cup (½ stick) unsalted butter, cut into small pieces

½ teaspoon crushed red pepper flakes plus more for serving

Kosher salt and freshly ground black pepper

12 oz. bucatini or spaghetti

Finely grated Parmesan (for serving)

PREPARATION

Preheat oven to 425°. Combine tomatoes (crushing them with your hands), garlic, anchovies, butter, and ½ tsp. red pepper flakes in a 13×9” baking dish; season with salt and black pepper. Roast, tossing halfway through, until garlic is very soft and mixture is jammy, 35–40 minutes. Using a potato masher or fork, mash to break up garlic and tomatoes.

Meanwhile, cook pasta in a large pot of boiling salted water, stirring occasionally, until al dente. Drain, reserving ½ cup pasta cooking liquid.

Return pasta to pot and add tomato sauce and pasta cooking liquid. Cook over medium-high heat, tossing until sauce coats pasta, about 3 minutes. Serve topped with Parmesan and more red pepper flakes.

DO AHEAD: Tomato sauce can be made 4 days ahead. Let cool; cover and chill. Reheat before mixing with pasta.

via Bucatini with Butter-Roasted Tomato Sauce – Bon Appétit.

Genetic testing raises hope for lung cancer treatments

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Lung cancer is one of the hardest cancers to treat

 

Offering genetic testing to lung cancer patients can potentially save lives, research suggests.

A study of 5,000 patients found genetic profiling of lung tumours boosted survival rates through better targeting of chemotherapy drugs.

The findings, reported in Science Translational Medicine, pave the way for personalised medicine.

Cancer Research UK said matching patients to a personalised treatment is still in its infancy.

The standard way to diagnose lung cancer is to look at cells from a tumour under the microscope.

On this basis, lung cancer can be classified into different tumour types, which helps doctors make decisions about the best treatment to offer.

However, in recent years scientists have made progress towards understanding how cancer can be better treated by matching drugs to the genetic make-up of a tumour.

A team led by Dr Roman Thomas, of the Max Planck Research Group in Cologne, Germany, carried out genetic testing on lung tumour samples from about 5,000 patients to spot genetic differences in lung cancer cells.


Our findings provide support for broad implementation of genome-based diagnosis of lung cancer”

Dr Roman ThomasMax Planck Research Group

They found that while some tumours look similar under the microscope, they actually belong to different subgroups.

Patients who received therapy based on genetic profiling of their tumours had a better prognosis, the study revealed.

Diagnostic genetic testing of lung cancer, combined with tailored treatment, may improve patient survival in the future, say the researchers.

“Our findings provide support for broad implementation of genome-based diagnosis of lung cancer,” they report in Science Translational Medicine.

Commenting on the research, Dr Sarah Hazell, Cancer Research UK’s senior science information officer, said the way scientists think about cancer is changing.

“This research highlights a growing trend of using drugs matched to the individual genetic profile of a tumour,” she said.

“For lung cancer though, it’s too early to claim a victory, as it’s still one of the hardest to treat cancers, and matching patients to a personalised treatment is still in its infancy. ”

Some 42,000 people have lung cancer diagnosed in the UK annually, with about 35,000 deaths from the disease.

Lung cancer is often diagnosed at a late stage, which makes it difficult to treat.

via BBC News – Genetic testing raises hope for lung cancer treatments.

Internet chatrooms can help those in distress, says study

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The negative influence of the internet has received widespread coverage this year

 

Internet forums and chatrooms can have positive effects that should be more widely acknowledged, experts say.

The call comes after Oxford University researchers carried out an analysis of 14 different studies looking at how young people use the internet.

The review – published in the Plos One journal – said a number of studies had found a link between internet use and self-harm and suicide.

But it said others had found the internet could be a positive influence.

The dangers of internet use have received widespread coverage this year. In one case, in August, 14-year-old Hannah Smith from Leicestershire was found hanged after she had been sent abusive messages on a social networking site.

Since then research by the NSPCC has suggested a fifth of 11 to 16-year-olds have had negative experiences using the internet.

‘Socially isolated’

The Oxford University research highlighted a number of dangers from internet use, including the normalising of self-harm and the risk of bullying.

It also said there was a “strong link” between internet forums and an increased risk of suicide in particular.


Rather than concentrating primarily on ways of blocking and censoring such sites, we should think about online opportunities to reach out to people in emotional distress”

Joe FernsSamaritans

But the researchers said some studies had shown that internet forums could support and connect socially isolated people.

There were also examples where forum users encouraged positive behaviour, advised others to seek help and congratulated each other for not harming themselves.

Report author Prof Keith Hawton said: “Communication via the internet and other electronic means has potential roles in both contributing to and preventing suicidal behaviour in young people.

“The next step is going to be development of therapeutic interventions using these channels of communication, especially to access those who do not seek help from clinical services.”

Joe Ferns of the Samaritans added: “We should acknowledge that many people are using suicide forums and chatrooms to anonymously discuss their feelings of distress and despair, including suicidal thoughts, which may have a positive impact on the individual. They may be expressing feelings that they have never disclosed to anyone in their offline lives.

“Rather than concentrating primarily on ways of blocking and censoring such sites, we should think about online opportunities to reach out to people in emotional distress.”

via BBC News – Internet chatrooms can help those in distress, says study.

New York to raise cigarette sale age

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The bill’s supporters say a higher age limit stops young people developing smoking habits

New York City Council has voted to raise the minimum age for buying cigarettes from 18 to 21.

New York will now become by far the most populous place in the US to impose such a high age limit, the Associated Press reports.

The new age limit includes electronic vapour cigarettes.

Across the US there is a minimum age for smoking of 18. Some states have raised the limit to 19 and at least two other towns have raised it to 21.

The bill’s sponsor, City Councilman James Gennaro, said it would “literally save many, many lives”.

Mr Gennaro, whose mother and father died from tobacco-related illnesses, said: “I’ve lived with it, I’ve seen it… but I feel good today.”

Critics of the measure have argued that young people may turn to the black market for cigarettes.

New York mayor Michael Bloomberg, who supported the bill, has 30 days to sign it into law. The measure would then come into effect after 180 days.

“We know that tobacco dependence can begin very soon after a young person first tries smoking so it’s critical that we stop young people from smoking before they ever start,” Mr Bloomberg said in a statement.

A plan by Mr Bloomberg to make shops keep cigarettes out of public view was shelved earlier this year.

via BBC News – New York to raise cigarette sale age.

HIV antibodies ‘have potent impact’

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A potential new HIV treatment has a “profound and unprecedented” impact on the virus, according to animal studies published in the journal Nature.

 

Potent antibodies were able to wipe a hybrid of human and monkey immunodeficiency viruses from the bloodstream of monkeys within days.

The findings could “revolutionise” the search for an HIV cure, say experts.

The US researchers said trials in patients with HIV now needed to take place.

The immune system produces precisely targeted antibodies to take out HIV, but the virus is able to rapidly mutate to evade the immune assault.


The effect with these potent antibodies is profound and unprecedented. It’s probably as large an antiviral therapeutic effect as has ever been seen”

Prof Dan BarouchHarvard Medical School

However, some antibodies have been discovered that target the “conserved” parts of HIV – those that the virus struggles to change because they are vital for it to function.

‘Undetectable’

Two groups, from Harvard Medical School and the National Institute of Allergy and Infectious Diseases, performed the first trials of these antibodies.

They used rhesus macaques that had been infected with simian-human immunodeficiency virus (SHIV), a blend of HIV and the monkey equivalent.

Data from the Harvard team showed that injection of the antibodies drove SHIV from the bloodstream until it reached undetectable levels after three to seven days.

The effect lasted for one to three months, but in three monkeys the virus did not return to the blood during the 250-day study.

Prof Dan Barouch told the BBC: “The effect with these potent antibodies is profound and unprecedented. It’s probably as large an antiviral therapeutic effect as has ever been seen.

“But we have to make sure we don’t overhype and the limitation is the study is in animals, not humans.”

The antibodies were also able to attack the virus in some tissues. Drugs can assault the virus in the blood during normal HIV treatment, but the virus can hide in other parts of the body.

These early findings raise the prospect of using antibodies to clear these tissues as well.

Similar results were produced by the team at the National Institute of Allergy and Infectious Diseases

‘Revolutionise’

HIV infection is incurable, although taking a daily dose of medication can keep the virus in check, giving patients a near-normal life expectancy.

The antibodies will be tested in human clinical trials and if successful they could be used alongside antiretroviral drugs as a treatment.

It may also be possible to devise a vaccine that could train the immune system to produce these antibodies.

However, both these ideas are dependent on human trials being successful.

Commenting on the findings, Prof Louis Picker and Prof Steven Deeks said: “The findings of these two papers could revolutionise efforts to cure HIV.”

However, they warned that HIV was so prone to mutation that it was “likely that some people will harbour viruses that are resistant to one or more” of the antibodies.

via BBC News – HIV antibodies ‘have potent impact’.

補鈣迷思!大骨湯加醋助鈣溶出?

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在傳統的觀念中,認為在所謂的骨頭湯中加醋,確實幫助鈣質油離而出。但究竟要加多少醋,熬煮多久,幫助釋放得量有多少,沒有確切的研究。

 

網路上流傳在熬煮大骨湯、排骨湯時,在湯中加入一小匙醋,有助於骨頭中鈣質流出的說法。不過這個方式真的有效嗎?營養師表示,在傳統的觀念中,認為在所謂的骨頭湯中加醋,確實幫助鈣質游離而出。但究竟要加多少醋,熬煮多久,幫助釋放的量有多少,沒有確切的研究。

鹿港基督教醫院陳紋慧營養師指出,熬煮大骨湯的同時,加醋有助於鈣質溶出的方式,在理論上是合理、可行的。不過,實際執行卻不容易,到底能夠幫助溶出多少的量、加多少量才有效果,是否會影響湯品風味,不得而知。

另外傳統觀念認為多喝所謂的骨頭湯,能夠幫助人體從中吸收到較多鈣質的說法並不正確。事實上,民眾就算喝下10碗以上的骨頭湯,也不夠補足人體一天所需的鈣質。民眾想要達到每日鈣質的建議攝取量,還是要透過均衡的飲食來攝取。

補鈣首選 脫脂牛奶

陳紋慧營養師表示,為達到身體骨骼、機能的正常運作。成年人每天要攝取1000mg的鈣質,老年人、發育中青少年,由於鈣質流失速度快、成長需求等因素,則應攝取1200mg的鈣質。但依現在民眾普遍外食,營養攝取不均衡的情況下,要達到這樣的鈣質含量攝取並不容易。

每1c.c的牛奶,約有1mg的鈣質含量。換算之下,每天喝2杯牛奶就能輕鬆攝取500mg的鈣質。

每1c.c的牛奶,約有1mg的鈣質含量。換算之下,每天喝2杯牛奶就能輕鬆攝取500mg的鈣質。

 

因此,還是建議民眾每天喝1.5杯至2杯(每杯約200ml)的牛奶,來補足人體每日對鈣質的需求。根據衛福部提供的數據顯示每1c.c的牛奶,約有1mg的鈣質含量。換算之下,每天喝2杯牛奶就能輕鬆攝取500mg的鈣質,相較於吃下100g的小魚干、芝麻容易許多。

但要注意的是,成年人、中老人在選擇牛奶時,應挑選低脂或脫脂的牛奶飲用,才不會攝取過量的不飽和脂肪,以及熱量,增加心血管疾病發生的風險。只要把握以上原則,就能輕鬆達到補鈣的效果。

綠色蔬食 讓你輕鬆補鈣

另外,除了從牛奶中攝取所需的鈣質外,民眾也可以透過多食用鈣質含量高的綠色蔬食來補充鈣質的攝取。包括香椿、芥蘭菜、芹菜、莧菜、紅鳳菜、小白菜、黑木耳等,每100公克的含量也有100毫克的鈣質含量,民眾可以在日常多加攝取,都有助於增加鈣質的攝取。

而蔬菜自身當中的所含有的維生素D的成份,也會成為身體運輸鈣質的載體,幫助腸道對於鈣質的吸收,將食用的鈣質,有效吸收到人體內,幫助生理機能的正常運作。

【營養師小叮嚀】:

由於鈣質進入人體後,並不會馬上被吸收利用,而是需要經由維生素D轉化,才會被吸收儲存。所以,除了在日常多攝取含有鈣質的食物外,建議民眾每天曬10至15分鐘的太陽,來加速維生素D的產生。利用維生素D是鈣質吸收載體的作用,幫助攝取的鈣質能夠更有效的被吸收利用。

via 補鈣迷思!大骨湯加醋助鈣溶出? | 20131031 | 華人健康網.

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