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Archive for September 1, 2013

Getodo

getodo

Getodo – Easy to-do lists and tasks (4 stars with 105 User Ratings) 
iPhone App 
$0.99 → Free 

Getodo is an iPhone task management app that connects you and other users and allows you to create tasks to complete for one another. Did your husband forget the milk? Send him a reminder via Getodo and it will pop up on his iPhone. You do have to create an account, but once you’ve done that, you’ll find that the incredibly easy and intuitive gesture based controls (similar to Clear, another popular to-do app) will have you acting like a “get things done” pro in no time. Grab it today for yourself and your friends/family and get things done.

via Best Free Apps of the Day on 8/31. AvgNite Cam, HT Recorder for iPad, Lens Lab, & More! | App Chronicles.

Chicken Tikka Masala

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INGREDIENTS

6 garlic cloves, finely grated

4 teaspoons finely grated peeled ginger

4 teaspoons ground turmeric

2 teaspoons garam masala

2 teaspoons ground coriander

2 teaspoons ground cumin

1 1/2 cups whole-milk yogurt (not Greek)

1 tablespoon kosher salt

2 pounds skinless, boneless chicken breasts, halved lengthwise

3 tablespoons ghee (clarified butter) or vegetable oil

1 small onion, thinly sliced

1/4 cup tomato paste

6 cardamom pods, crushed

2 dried chiles de árbol or 1/2 teaspoons crushed red pepper flakes

1 28-ounce can whole peeled tomatoes

2 cups heavy cream

3/4 cup chopped fresh cilantro plus sprigs for garnish

Steamed basmati rice (for serving)

PREPARATION

 

  • Combine garlic, ginger, turmeric, garam masala, coriander, and cumin in a small bowl. Whisk yogurt, salt, and half of spice mixture in a medium bowl; add chicken and turn to coat. Cover and chill 4-6 hours. Cover and chill remaining spice mixture.
  • Heat ghee in a large heavy pot over medium heat. Add onion, tomato paste, cardamom, and chiles and cook, stirring often, until tomato paste has darkened and onion is soft, about 5 minutes. Add remaining half of spice mixture and cook, stirring often, until bottom of pot begins to brown, about 4 minutes.
  • Add tomatoes with juices, crushing them with your hands as you add them. Bring to a boil, reduce heat, and simmer, stirring often and scraping up browned bits from bottom of pot, until sauce thickens, 8-10 minutes.
  • Add cream and chopped cilantro. Simmer, stirring occasionally, until sauce thickens, 30-40 minutes.
  • Meanwhile, preheat broiler. Line a rimmed baking sheet with foil and set a wire rack inside sheet. Arrange chicken on rack in a single layer. Broil until chicken starts to blacken in spots (it will not be cooked through), about 10 minutes.
  • Cut chicken into bite-size pieces, add to sauce, and simmer, stirring occasionally, until chicken is cooked through, 8-10 minutes. Serve with rice and cilantro sprigs. DO AHEAD: Chicken can be made 2 days ahead. Cover; chill. Reheat before serving.

via Chicken Tikka Masala – Bon Appétit.

‘Molecular basis’ for jet lag found

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Scientists believe they have figured out why it takes us so long to adapt when we travel to new time zones.

Researchers at Oxford University say they have found the “molecular brakes” that prevent light resetting the body clock when we fly – causing jet lag.

Experiments, reported in the journal Cell, showed “uncoupling” these brakes in mice allowed them to rapidly adapt.

Researchers hope the discovery will help find new drugs for jet lag and mental health treatments.

The body clock keeps us in tune with the pattern of day and night. It means we sleep at night, but also affects hunger, mood and blood pressure.

Light acts like a reset button to keep the clock to time, but when we fly around the world it takes time for our body clocks to adjust. The resulting fatigue, which can last for days, is known as jet lag

Master clock

The research team, funded by The Wellcome Trust, was trying to figure out why people do not instantly adapt. They looked in mice as all mammals have the same core body clock mechanisms.

They focused on the “master clock” in a part of the brain, which keeps the rest of the body in sync, called the suprachiasmatic nuclei

They were looking for sections of DNA that changed their activity levels in response to light.


This provides a molecular basis for jet lag and as a result new targets for potentially developing new drugs”

Prof Russell FosterOxford University

They found a huge numbers of genes were activated, but then a protein called SIK1 went round turning them all off again. It was acting as a brake by limiting the effect of light.

Experiments to reduce the function of SIK1 meant the mice could rapidly adjust their body clock when it was shifted six hours – the equivalent of a flight from the UK to India.

Reset

Prof Russell Foster told the BBC: “We reduced levels by 50-60%, which is big enough to get a very, very big effect. What we saw was the mice would actually advance their clock six hours within a day [rather than taking six days for untreated mice].

“We’ve know there’s been a brake on the clock for some time, but we had absolutely no idea what it is, this provides a molecular basis for jet lag and as a result new targets for potentially developing new drugs.”

He said some mental health disorders including schizophrenia were linked to an out-of-tune body clock, so these findings may open up new areas for research.

The brakes are likely to be in place to prevent the body clock from becoming erratic and being reset by artificial or moon light.

Dr Akhilesh Reddy, a specialist in the body clock, at the University of Cambridge, was very confident that treatments would follow as “it is a very drugable target and I would suspect there are lots of potential drugs already developed”.

He told the BBC: “We have known a lot about the basis of jet lag and why it occurs.

“This shows how you can get into the brain and manipulated the clock, which is why this study is important.

“We have drugs which can make the clock shorter or longer, what we need is to shift it to a new time zone and that is what they have done.”

via BBC News – ‘Molecular basis’ for jet lag found.

Blueberries, not fruit juice, cut type-2 diabetes risk

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Blueberries and apples contain high levels of anthocyanins

Eating more fruit, particularly blueberries, apples and grapes, is linked to a reduced risk of developing type-2 diabetes, suggests a study in the British Medical Journal.

Blueberries cut the risk by 26% compared with 2% for three servings of any whole fruit – but fruit juice did not appear to have the same effect.

The research looked at the diets of more than 187,000 people in the US.

But Diabetes UK said the results of the study should be treated with caution.

Researchers from the UK, US and Singapore used data from three large studies of nurses and health professionals in the US to examine the link between fruit consumption and the risk of contracting type-2 diabetes.


What is type-2 diabetes?

Diabetes is an incurable condition in which the body cannot control blood sugar levels, because of problems with the hormone insulin.

In type-2 diabetes, either the pancreas cells do not make enough insulin, or the body’s cells do not react properly to it. This is known as insulin resistance.

What is diabetes?

In these studies, 6.5% of participants (12,198 out of 187,382) developed type-2 diabetes.

The studies used food frequency questionnaires to follow up the participants every four years, asking how often, on average, they ate a standard portion of each fruit.

The fruits used in the study were grapes or raisins, peaches, plums or apricots, prunes, bananas, cantaloupe, apples or pears, oranges, grapefruit, strawberries and blueberries.

The researchers’ analysis of the data showed that three servings per week of blueberries, grapes and raisins, and apples and pears significantly reduced the risk of type-2 diabetes.

While all fruit was shown to reduce the risk, these fruits appeared to be particularly effective.

The researchers said this could be due to the fact these fruits contain high levels of anthocyanins, which have been shown to enhance glucose uptake in mice. The same fruits contain naturally-occurring polyphenols which are known to have beneficial effects.


The juicing process gets rid of the fruit, just leaving fluids which are absorbed more quickly.”

Prof Qi SunHarvard Medical School

In the study paper, they wrote: “Fruits have highly variable contents of fibre, antioxidants, other nutrients, and phytochemicals that jointly may influence the risk.”

But the glycaemic load of different types of fruit – the quality and quantity of carbohydrate they contain – did not fully explain the results, the study said.

Juice effect

When they looked at the effects of fruit juice consumption, the researchers found a slightly increased risk of type-2 diabetes.

The study calculated that replacing weekly fruit juice consumption with whole fruits could bring health benefits.

For example, replacing fruit juice with blueberries could reduce the risk of contracting type-2 diabetes by 33%, with grapes and raisins by 19%, apples and pears by 13% – and with any combination of whole fruit by 7%.

Replacing fruit juice with oranges, peaches, plums and apricots had a similar effect.

Qi Sun, study author and assistant professor at Harvard School of Public Health, said, in general, fruit juices contained less of the beneficial compounds found in whole fruits.

Pouring orange juice
Whole fruits are preferable to fruit juice, the study says

“The juicing process gets rid of the fruit, just leaving fluids which are absorbed more quickly, causing blood sugars and insulin levels to rise if they contain sugars.

“To try to minimise the risk of type-2 diabetes as much as possible it is reasonable to reduce fruit juice consumption and increase consumption of whole fruits.”

Experts say the best way to reduce your risk of developing type-2 diabetes is to eat a balanced, healthy diet that includes a variety of fruits and vegetables and to be as physically active as possible.

‘Unreliable’

Dr Matthew Hobbs, head of research for Diabetes UK, said the study provided further evidence that eating plenty of whole fruit was a key part of the balanced diet that will minimise the risk of developing type-2 diabetes.

However, he said the links between type-2 diabetes and specific types of fruit or fruit drinks should be treated with caution.

“Some of the findings are based on a number of assumptions and models which may have distorted the results significantly.

“For example, the researchers used surveys to ask participants how often they ate certain foods. This type of survey can often be unreliable as people are more likely to remember certain types of food.”

Kamlesh Khunti, professor of primary care diabetes and vascular medicine at the University of Leicester, said the large study showed that eating any fruit is good.

“Eating all kinds of fruit works and there is still a reduction in risk.

“The government recommends eating five portions of fruit and vegetables every day.”

via BBC News – Blueberries, not fruit juice, cut type-2 diabetes risk.

Insomniacs’ brains lose focus, scans suggest

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Brain scans of people who say they have insomnia have shown differences in brain function compared with people who get a full night’s sleep.

Researchers at the University of California, San Diego, said the poor sleepers struggled to focus part of their brain in memory tests.

Other experts said that the brain’s wiring may actually be affecting perceptions of sleep quality.

The findings were published in the journal Sleep.

People with insomnia struggle to sleep at night, but it also has consequences during the day such as delayed reaction times and memory.

The study compared 25 people who said they had insomnia with 25 who described themselves as good sleepers. MRI brain scans were carried out while they performed increasingly challenging memory tests.

One of the researchers, Prof Sean Drummond, said: “We found that insomnia subjects did not properly turn on brain regions critical to a working memory task and did not turn off ‘mind-wandering’ brain regions irrelevant to the task.

“This data helps us understand that people with insomnia not only have trouble sleeping at night, but their brains are not functioning as efficiently during the day.”

A sleep researcher in the UK, Dr Neil Stanley, said that the quality of the sleep each group was having was very similar, even though one set was reporting insomnia.

He said: “What’s the chicken and what’s the egg? Is the brain different and causing them to report worse sleep?

“Maybe they’re perceiving what happened in the night differently; maybe what is affecting their working memory and ability to focus on the task at hand is also causing insomnia.”

via BBC News – Insomniacs’ brains lose focus, scans suggest.

Addenbrooke’s Hospital ‘shackled’ to fast food contract

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The hospital’s food court includes a hamburger chain and a pizza chain

 

The boss of a Cambridge hospital has told the BBC he would like to ban fast food from the site, but is “contractually shackled” to provide it.

Dr Keith McNeil, chief executive of Addenbrooke’s, already plans to ban smoking at the site from January.

He was asked if he also planned to ban fast food, and remove certain outlets from the hospital’s food court.

Dr McNeil said: “If we could we would, but at the moment we’re contractually shackled… but that’s next, yes.”

The hospital has a number of cafes and restaurants, including a burger chain and a pizza chain.

Cambridge University Hospitals NHS Foundation Trust, which runs Addenbrooke’s, did not want to comment further on Dr McNeil’s statement.

But a spokesman said the hospital offered a number of healthy food options to staff, visitors and patients using the food court.

He added: “We continue to work with our retail partners to ensure there are balanced food choices available… and are implementing further healthy options in the very near future.”

The hospital’s contract with Gentian, a company which owns and manages retail facilities within NHS hospitals, runs until 2024.

via BBC News – Addenbrooke’s Hospital ‘shackled’ to fast food contract.

伊比力斯兒發作 別在嘴巴塞東西

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台灣約有14萬名伊比力斯患者需要社會關懷,藥廠致贈紫色頭巾支持公益活動。(圖片提供/台灣兒童伊比力斯協會)

 

三五好友找個籃球場軋籃球「鬥牛」,或是到運動中心健身游泳,都是輕鬆自在的事情,可是有一群弱勢的族群卻往往被排除在外,不能自由自在的在運動場所盡情奔跑、舒展筋骨,他們是「伊比力斯兒」。根據一項調查顯示,有約3成的民眾認為伊比力斯兒不適合從事運動,可見觀念偏差必需改善。

根據2002~2003年健保局統計,台灣約有14萬名伊比力斯患者。為了多關懷這一些兒童,台灣兒童伊比力斯協會針對444位民眾進行問卷調查,結果發現,有約3成的民眾認為伊比力斯兒不適合從事運動,有超過4成的民眾認為運動會使伊比力斯兒病情加重。這些錯誤的刻板印象,使得伊比力斯兒在運動上受到很大的限制,也剝奪了他們快樂運動的機會。

伊比力斯兒發作 逾7成民眾感害怕

此外,問卷調查也發現,介意與伊比力斯兒一起運動的民眾中,有7成5的民眾害怕伊比力斯兒會忽然發作,認為發作很可怕,甚至有2成5的民眾認為伊比力斯兒會傳染。這些錯誤的觀念導致伊比力斯兒因遭受到排擠,到戶外參加各項運動的機會愈來愈低。

伊比力斯兒可運動 適合田徑游泳球類

醫師們建議,只要發作在合理的控制下,而且體力可以負荷,不要過度運動,伊比力斯兒不妨多參加戶外活動,例如:田徑、游泳、球類活動均可,較不建議參加攀岩或騎馬。參與一般戶外活動的時間和運動量可以慢慢逐步增加,同時兼顧孩子的體能狀況。

當碰到「伊比力斯兒」真正發作時,應該如何正確處置呢?調查發現有超過5成的民眾認為伊比力斯兒發作時,應該塞東西進入伊比力斯兒童嘴巴,或應該強行約束或壓制伊比力斯兒,這些都是錯誤的觀念,這樣容易在伊比力斯兒發作時造成受傷。

 

台灣兒童伊比力斯協會特別挑選今年最夯的棒球運動,在青少年育樂中心舉辦伊比力斯兒童樂樂棒球營。(圖片提供/台灣兒童伊比力斯協會)

台灣兒童伊比力斯協會特別挑選今年最夯的棒球運動,在青少年育樂中心舉辦伊比力斯兒童樂樂棒球營。(圖片提供/台灣兒童伊比力斯協會)

 

【伊比力斯兒發作 協助2口訣】:

★口訣一: 不要慌張叫叫他

1.保持鎮定、不要慌張。

2.確認小朋友的意識是否清醒。

★口訣二:輕輕側放保護他

1.協助小朋友躺下側臥,移開旁邊的障礙物及鬆開衣物,製造一個安全的環境,讓小朋友安全地發作結束。

2.不可拿手指頭或塞任何東西進小朋友的口中。

3.不需要大聲叫喊、用力搖晃或按壓小朋友,只要在一旁陪伴小朋友完全清醒後才可以離開。

台灣兒童伊比力斯協會特別挑選今年最夯的棒球運動,青少年育樂中心舉辦伊比力斯兒童樂樂棒球營,讓伊比力斯兒可以體驗打棒球的樂趣,此外,人氣氣象主播王淑麗也特別到現場化身啦啦隊,為伊比力斯兒加油。藥廠獻愛心贊助具有特殊意義的紫色頭巾,並由公司的棒球隊擔任一日志工,帶領伊比力斯兒共同快樂的打棒球。

via 伊比力斯兒發作 別在嘴巴塞東西 | 20130831 | 華人健康網.

轉大人調體質 黃金期10歲開始

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兒童從10歲開始到18歲左右,藉由中藥調理,對以後身高發育產生很大的影響。

 

早晚天氣涼意湧上心頭,9月7至9日節氣上為白露,而根據傳統中醫數千年的經驗,秋季白露開始,是適合進行轉骨調理的季節,家長應該怎麼幫孩子補身體改善體質,讓孩子身高發育不落人後?中醫師表示,飲食均衡最重要,把握黃金長高期間進行中醫調理,也是不錯的選擇!

中醫師黃聖哲表示,隨著現代人營養充足,生活品質進步,台灣青年男性平均身高172.8公分,青年女性平均身高也有160.5公分,比起以往成長許多,擁有較高的身高在職場與人際關係上也較有優勢,因此許多家長很擔心自己的下一代會矮人一截,所以轉向中醫轉骨體質調理。

轉骨好時機 從10歲開始

所謂「轉骨」,就是藉由中醫藥的輔助,使小孩從兒童期成功「轉大人」的過程。什麼時候轉骨療效較好?黃聖哲中醫師表示,兒童從10歲開始到18歲左右,男孩約在喉結出現前後,女孩約在胸部發育,初經來潮前後開始生長潛力最大,藉由中藥調理改善代謝機能及過敏性體質,並加強腸胃吸收、提昇筋骨的伸展性,同時對以後身高發育產生很大的影響。

轉骨調理體質 連續2至3個月

秋季白露開始,是適合進行轉骨調理的季節,因為秋季天氣轉涼,身體進入休養收藏狀態,此時調理可達到較好的吸收效果,為來年春季發育做好準備,把握對的時機根據醫師診斷處方,依個人體質連續調理2到3個月左右,轉骨成功的機會較大。

 

轉骨多作跳躍與伸展運動,如跳繩、跳高、打籃球、瑜珈等,對發育都有助益。

轉骨多作跳躍與伸展運動,如跳繩、跳高、打籃球、瑜珈等,對發育都有助益。

 

轉骨注意4要點 飲食運動兼顧

1.應注意孩子的飲食,營養要均衡,多補充天然鈣質如牛奶、優酪乳、小魚乾、深色蔬菜等。

2.避免攝取冰飲與油炸食物,以及含糖量高的零食,以免影響長高。

3.孩子應該養成晚間11點前入睡的好習慣。

4.多作跳躍與伸展運動,如跳繩、跳高、打籃球、瑜珈等,對發育都有助益。

測骨齡僅參考 把握黃金長高期

有許多家長關心骨齡是絕對的嗎?黃聖哲中醫師表示,臨床有不少被依骨齡判定幾乎無法長高,但經調理後突破瓶頸的例子,測量骨齡的確可當參考但不是絕對,中醫轉骨是依據個人臟腑狀況調理,若能把握黃金長高期間請專業中醫師調理,即有機會改變先天體質,一圓長高夢想。

via 轉大人調體質 黃金期10歲開始 | 20130831 | 華人健康網.

新觀念!防心肌梗塞 先降內臟脂肪

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預防心肌梗塞發生,更重要的是降低身體內臟脂肪的比例。

 

義大犀牛隊總教練徐生明日前因心肌梗塞發作送醫不治而辭世,留下世人遺憾。預防心肌梗塞,除了控制飲食,以低鹽、多蔬果、少攝取肥肉與動物內臟為原則,更重要的是降低身體內臟脂肪的比例,從代謝症候群的風險防堵,就能遠離心肌梗塞威脅。

內臟脂肪與心肌梗塞之間有何關聯性?主要是內臟脂肪堆積會讓多餘的三酸甘油酯與低密度膽固醇(壞膽固醇)滲入動脈內壁,逐漸氧化、變質,使血管壁變厚、失去彈性,形成動脈硬化,進而演變成心肌梗塞、中風等致命性疾病。

內臟脂肪型肥胖 容易誘發心肌梗塞

有內臟脂肪型肥胖的人,糖尿病的發病率是一般人的7~9倍,心肌梗塞、中風的致死率更高達3倍。家醫科醫師納祖德表示,要降低內臟脂肪,正確的運動是不二法門;而運動的關鍵不在激烈程度,而在於能否真正燃燒脂肪。目前已有燃脂心率錶,能檢視消耗的卡路里等運動狀態,並協助個人在最適當燃脂區運動,而且是以簡單的健走方式進行,不致度疲憊,並達到運動消耗內臟脂肪的效果。

內臟脂肪如何檢視?量腰圍是個最簡單的檢測指標,關心自己與家人就是幫他(她)量腰圍,女性超過80公分、男性超過90分鐘即為警訊,一定要特別注意。

 

維持每周3次、每次45分鐘的加強心肺有氧運動與重量訓練,可消除20%的內臟脂肪。

維持每周3次、每次45分鐘的加強心肺有氧運動與重量訓練,可消除20%的內臟脂肪。

 

降低內臟脂肪發生 4點日常保健

1.攝取膳食纖維:膳食纖維有助排泄順暢,並吸收有害物質和膽固醇,重點是不想讓內臟脂堆肪,可以多吃膳食纖維,包括燕麥、綠豆、蕃茄、葡萄柚等。

2.吃五色蔬菜:每天維持五蔬果,最好加熱後食用,可提高代謝,並燃燒內臟脂肪。

  1. 肌肉訓練:通過肌肉訓練能消耗掉內臟脂肪,這樣做也可以增加人體的基礎代謝率,使肌肉細胞有活力。

4.有氧運動:根據美國《預防醫學》(Journal of Preventive Medicine)雜誌發表的一項研究顯示,維持每周3次、每次45分鐘的加強心肺有氧運動與重量訓練,可消除20%的內臟脂肪。

預防內臟脂肪型肥胖 先了解屬性

一旦內臟脂肪開始囤積,會使身體從小腹突出演變成高血壓、高血糖、高血脂等代謝性疾病,甚至致命性的心肌梗塞、腦中風等疾病。因此,平時應該預防「內臟脂肪型肥胖」,並了解肥胖是屬於「內臟脂肪型肥胖」還是「皮下脂肪型肥胖」,最好趁早預防。

內臟脂肪雖然是危險的脂肪,幸好具有容易甩掉的特性,能在代謝症候群階段就杜絕病症的發展,避免慢性病、動脈硬化,甚至致命性疾病發生。因此平時更應該做好以上日常保健動作,避免內臟脂肪上身。

via 新觀念!防心肌梗塞 先降內臟脂肪 | 20130831 | 華人健康網.

靈芝多醣抗癌關鍵 答案:岩藻醣

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中研院實驗證實靈芝多醣中一種叫做「岩藻醣」的成分,能夠誘導出抗體、進而消滅癌細胞。(圖片/取材自農委會)

 

許多人都知道靈芝多醣具有強化免疫、抗癌的效果,為了解開關鍵原因,中研院基因體中心副研究員吳宗益帶領團隊,經過實驗證實關鍵在於靈芝多醣中一種叫做「岩藻醣」的成分,能夠誘導出抗體、進而消滅癌細胞,因而破解解這個謎團。

先前陽明大學許先業教授的研究團隊已發現將F3打入產生肺癌的小鼠時可有效的抑制腫瘤的生長,但其抗癌的機理利用已知的免疫學知識一直無法獲得有效的解釋。

靈芝多醣的岩藻醣成份 能有效抑制腫瘤

中研院基因體中心副研究員吳宗益帶領的團隊,實驗證實關鍵在於靈芝多醣中一種叫做「岩藻醣」的成分,能夠誘導出更多對抗Globo H的抗體,並且可更有效的抑制腫瘤的生長,且結果顯示岩藻醣的存在是靈芝多醣抗癌的關鍵,若將岩藻醣去除則活性會大幅度的下降。研究成果登上最新一期美國國家科學院會報(PNAS),並獲得特別撰文報導。

【小辭典/岩藻醣(Fucose)】

岩藻醣是身體細胞對細胞通訊得到最佳的功能所需8種必須醣類其中之一,L型岩藻醣是唯一通用的型態,D型岩藻醣是一種合成的半乳醣相似體,岩藻醣不應該和果糖混淆不清,果糖是一種在水果和蜜蜂中可以發現的單糖。

岩藻醣結合的醣蛋白和醣脂質,是強而有力的免疫調節器,分布在巨噬細胞中,對免疫功能具有絕對的重要性,尤其對免疫系統過度活躍導致的自體免疫疾病。更在在許多疾病扮演重要的角色,包括癌症和癌症的蔓延。在抑制白血病和乳癌還有腫瘤的成長,岩藻醣和甘露醣是最有效的必須醣類。

岩藻糖較大量地存在於海藻及樹膠中,也發現於某些細菌的多糖中。岩藻醣在某些醫藥用的蕈類中也可發現到,例如海草灰、啤酒酵母。

via 靈芝多醣抗癌關鍵 答案:岩藻醣 | 20130831 | 華人健康網.

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