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Archive for April 5, 2013

New blood test may predict mortality rate in heart failure patients

Blood test which measures a new bio-marker of early heart disease called “GDF15” has the potential to reduce this risk.

A new blood test may predict if a patient who has heart failure can pull through, which can then help doctors in their treatment. And for the first time, it is being tested on Asian population.

SINGAPORE – A new blood test may predict if a patient who has heart failure can pull through, which can then help doctors in their treatment.

And for the first time, it is being tested on Asian population.

Heart failure – a condition where the heart becomes weak and fails to pump blood out efficiently – is the top cause of hospitalisation among the elderly in Singapore.

More than half of the patients with this condition die within five years.

But a blood test which measures a new bio-marker of early heart disease called Growth Differentiation Factor 15 (GDF15) has the potential to reduce this risk.

Results from an on-going study by researchers at the National University Health System of 394 heart failure patients showed that the higher the level of GDF15, the more likely the patients will die or are re-hospitalised within a year.

An interim analysis after one year showed that 118 patients were re-admitted for heart failure, while 35 patients died.

The study is expected to run for a further three years.

Currently, the factors which doctors use to determine heart failure outcome include age, functional status and a standard bio-marker called NT-proBNP.

Researchers believe that if this GDF15 marker reaches the clinical stage, it will improve accuracy of diagnosis.

Associate professor Carolyn Lam, a consultant at National University Heart Centre’s cardiac department, said: “A marker that tells the doctor who is going to do worse is important, because there are many effective therapies for heart failure that exist.

“In medical therapy, there are many classes of drugs. Each of these drugs is associated with side effects. So knowing who needs it more, will make us be more aggressive in making sure that we escalate the doses.”

Going forward, the research team plans to increase its pool of patients, as well as study the blood marker in more categories, such as gender and ethnicity.

– CNA/ck

http://www.channelnewsasia.com/news/singapore/singaporelocalnews/new-blood-test-may-predict-mortality-rat/627432.html

New centre for autistic children

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Permata Negara patron Datin Seri Rosmah Mansor (centre) checking out a model of the Permata Kurnia centre which will be built in Jalan Sentul, Kuala Lumpur, at an estimated cost of RM28 million. Pic by Fariz Iswadi Ismail

 

INTERVENTION PROGRAMME: Construction of Permata Kurnia likely to start in August with completion in 18 months

PUTRAJAYA : THE  Permata Kurnia centre, which is a  new programme under Per mata Negara, will help to teach  autistic children and address the prob lems faced by them.autistic children in the country.

Datin Seri Rosmah  Mansor, the Permata  Negara patron and, who is also  the prime minister’s  wife,  said it was timely  to have such a centre,  especially when the  country was heading to wards achieving the developed nation  status.

“In order for us to be a  developed nation, we  must have a systematic  and scientific centre to  address such issues and  Permata Kurnia would  be catering for autistic  children.

“It will also be a centre  where wewhich will teach par ents to understand their children  better and to help them to cope with their  disorderdisability,” said Rosmah during the  centre’s pre-launching event held at  Seri Perdana complex,   here, yesterday.

Permata Kurnia, to be built on a  1.05ha2.6-acre plotplot in Jalan Sentul, Kuala  Lumpur, at an estimated cost of and the approximate cost is  RM28 million, is, which is fully funded by the  government.

Construction of the centre is expected to start  in August with completion will take in 18  months to complete (Feb 2015).

The pre-launch of Per mata Kurnia was held in  conjunction with the World  Autism Day celebrated  celebration which is held on April 2 annually.

Rosmah said that even though autistic  children had special  cognitive abilities.

“Some of these chil dren are talented,  whether academically  or musically.

“So, with the interven tion programmes that would be pro vided by the centre, they  can be equipped with  skills that will help them  go through their lives as  normally as possible.” aside from developing their abilities.”

She said that the centre  would providebe providing three  types of services, name ly and they are full-time intervention, family and  support intervention and training  programmes.

They and would be designed to cater to  the needs of  parents and their children.

“For example, the full-time inter vention programme is for a catered to children  aged 4 to 6 who has been diagnosed with mild  autism.

“This early intervention pro gramme willwould be used to guide and help the chil dren toso that they would be ready for their formal edu cation.”  Rosmah added.

Rosmah added that the idea ofto  building the centre was conceived  during working visits to various autism cen tres in the United States and the  United Kingdom between Feb 4 and  Feb 11, 2013.

The objective of the working visits  was to learn and observe the im plementation of autism pro grammes in the centres.

Read more: New centre for autistic children – General – New Straits Times http://www.nst.com.my/nation/general/new-centre-for-autistic-children-1.248778#ixzz2PXzoSON5

上海1名与H7N9感染者密切接触者现发热等症状被隔离

昨验出有鸽子感染H7N9禽流感的上海松江区沪淮农副产品批发市场内,可见到活鸡在大铁笼内自由走动,到昨深夜,上海市下令扑杀所有场内禽鸟。

上海松江区沪淮农副产品批发市场内的鸽子昨虽验出感染H7N9禽流感,但至昨晚9时半,本报记者并未见到上海当局在市场内有任何防疫措施,部分档主如常点算存放在栏内的活家禽如鸡只。

禽流感预防及治疗方案

原标题:上海1名与H7N9感染者密切接触者出现发热等症状

新华网上海4月4日电(记者仇逸 李荣)记者从上海市卫生和计划生育委员会获悉,截至4日23时,上海共发现6例人感染H7N9禽流感确诊病例,死亡4例,2例正在救治之中,6例病例之间均无关联性。一名死亡病例的密切接触者中,有一人出现发热、流涕、咽痒等症状,已被隔离治疗。

上海H7N9死亡病例亲属因相似症状

患者于某4月3日经抢救无效死亡,4日下午,上海市疾病预防控制中心报告实验室检测结果为H7N9禽流感病毒核酸阳性。经调查,该病例的密切接触者共有31人,截至目前,1人出现发热、流涕、咽痒等症状,4日18点53分已转入上海市公共卫生临床中心隔离治疗,其他密切接触者均未发现有发热或呼吸道症状。

当日,国家禽流感参考实验室从上海市送检的松江区沪淮农副产品批发市场鸽子样品中检测到H7N9禽流感病毒。上海市农委当天已紧急部署相关禽流感防控措施,立即关闭沪淮农副产品批发市场活禽交易区,扑杀交易区内所有禽鸟。

据上海市农委人士说,按照农业部办公厅关于防控H7N9禽流感病毒传播的紧急通知要求,已将动物感染H7N9禽流感病毒作为一类动物疫病管理,立即启动应急预案。上海还将暂停这次检出H7禽流感病毒的闵行区景川菜市场、凤庄市场的活禽交易,并做好现场消毒工作。

凤凰网 http://news.ifeng.com/mainland/special/h7n9/content-3/detail_2013_04/05/23881391_0.shtml

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