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Back-to-School-Tomato-Kale-Macaroni-940x600

INGREDIENTS

  • 2 tablespoons olive oil, plus more
  • 2 ounces pancetta, chopped
  • 1 medium onion, chopped
  • 1 carrot, chopped
  • 1 celery stalk, chopped
  • 1 large Yukon Gold potato, peeled, cut into ½” pieces
  • Kosher salt, freshly ground pepper
  • 2 garlic cloves, finely chopped
  • 1 28-oz. can whole tomatoes, drained
  • 6 cups chicken broth
  • 1 bay leaf
  • 1 Parmesan rind
  • ½ bunch Tuscan kale, bottom stems trimmed, sliced into ½” strips (about 4 cups)
  • 1 cup cooked pasta, rice, and/or grains
  • Torn basil leaves and grated Parmesan (for serving)

PREPARATION


  • Heat oil in a Dutch oven or small stockpot over medium heat. Add pancetta and cook, stirring often, until pancetta is lightly browned around the edges and fat is partially rendered, about 5 minutes. Add onion, carrot, celery, and potato and season with salt and pepper. Cook, stirring often, until vegetables are softened and onion is translucent, 10–12 minutes. Add garlic and cook, stirring, until fragrant, about 2 minutes. Add tomatoes, lightly breaking them up with your hands as you add to the pot; add chicken broth, bay leaf, and Parmesan rind. Bring to a simmer, season with salt and pepper, and add kale. Simmer until potatoes and kale are tender, 10–15 minutes. Remove from heat and add pasta, rice, and/or grains. Serve with basil, grated Parmesan, and a drizzle of olive oil.

via Vegetable Soup Recipe – Bon Appétit.

tagjournal

Tag Journal: write your diary
(3.5 stars with 17 Ratings)
Universal App
$2.99 Free for a limited time

 

Whether or not you’re a writer, it’s a good thing to get your life and thoughts down on paper, whether as a means of therapy or to stretch your memory. For that sort of endeavor, there are plenty of apps to choose from, but we want to highlight Tag Journal for you today.

Tag Journal allows you to record your life in multiple media formats, such as the written word, photography, quick videos, notes, and even voice recordings. Hailed as one of the better journal apps out there by many media sources, you’ll find a veritable treasure trove of features to work with. Everything in Tag Journal syncs via iCloud so you can have all your data and entry notes together wherever you go, with whatever device you have on you at the time.

You can shoot photos and video from within the app, or even upload previously filmed and shot items from your device’s camera roll. Notes will have a time stamp on them, and you can sort and organize everything with colored tags so you’re able to differentiate what’s what. Other features include a built-in browser, photo effects to apply, and full-fledged searching. Download Tag Journal and get started on documenting your life better.

App Screenshots

via Tag Journal: Take videos, shoot photos, write notes, and record your voice with this all-in-one journal app | App Saga.

stone-fruit-cobbler-940x600
INGREDIENTS

FILLING

  • 3 pounds peaches, nectarines, or plums, each cut into 6 wedges
  • ½ cup granulated sugar
  • 2 tablespoons all-purpose flour
  • ¼ teaspoon kosher salt
  • 1 tablespoon kirsch (clear cherry brandy) or other fruit brandy (optional)

TOPPING AND ASSEMBLY

  • ½ cup all-purpose flour
  • ¾ teaspoon baking powder
  • ¼ teaspoon kosher salt
  • ½ cup (1 stick) unsalted butter, room temperature
  • oz. almond paste
  • ½ cup granulated sugar
  • 3 large eggs, room temperature
  • ½ cup sliced almonds
  • Powdered sugar and vanilla ice cream (for serving)

NUTRITIONAL INFORMATION

Calories (kcal) 340 Fat (g) 16 Saturated Fat (g) 7 Cholesterol (mg) 80 Carbohydrates (g) 46 Dietary Fiber (g) 3 Total Sugars (g) 36 Protein (g) 6 Sodium (mg) 150

PREPARATION


FILLING

  • Toss peaches, granulated sugar, flour, salt, and kirsch, if using, in a large bowl. Transfer to a 13×9” baking dish; set aside.

TOPPING AND ASSEMBLY

  • Preheat oven to 350°. Whisk flour, baking powder, and salt in a medium bowl. Using an electric mixer, beat butter, almond paste, and granulated sugar in a large bowl until light and fluffy, about 4 minutes. Add eggs one at a time, beating to blend after each. Mix in dry ingredients.
  • Drop dollops of batter over fruit (batter will even out during baking). Sprinkle with almonds. Place baking dish on a rimmed baking sheet and bake until topping is golden brown and fruit juices are thick and bubbling, 50–60 minutes. Let cobbler sit at least 20 minutes before serving. Dust with powdered sugar and serve with ice cream.

via Stone Fruit Cobbler Recipe – Bon Appétit.

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People saw their hair fully restored after just five months of treatment right

 

Scientists have completely reversed hair loss in three people by giving them a drug normally used to treat bone marrow disorders.

The patients had alopecia areata – a condition that can cause severe, patchy baldness that is difficult to treat.

But after five months of taking the medication ruxolitinib, all three saw total hair re-growth.

The findings from Columbia University Medical Center are published in the journal Nature Medicine.

‘Devastating disease’

Alopecia areata affects around two in every 1,000 people in the UK and is thought to be caused by the immune system attacking hair follicles.

The US scientists had previously identified a set of immune cells involved in the destruction of hair and conducted a number of successful trials in mice.

They then gave three patients with moderate to severe alopecia areata a twice daily dose of ruxolitinib.

This medication is already approved for use in bone marrow conditions in the United States and European Union.

All three patients had lost at least a third of their hair but saw dramatic hair growth within five months of therapy.

Lead researcher Dr Raphael Clynes said: “We’ve only begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with the disease.”

Prof David Bickers, a dermatologist at Columbia University who has treated many patients with the disease, said: “There are few tools in the arsenal for the treatment of alopecia areata that have any demonstrated efficacy.

“This is a major step forward in improving the standard of care for patients suffering from this devastating disease.”

Researchers say more work is now needed to see if the drug can be offered more widely.

Alopecia areata can occur at any age but is most often seen in teenagers and young adults.

It is not related to the more common male-pattern hair loss that is thought to be driven by hormones.

Scientists say as the mechanisms behind this condition are different, the therapy is less likely to prove effective for this more common problem.

via BBC News – Hair loss reversed in alopecia areata sufferers.

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Following earlier denials, Liberia has admitted that 17 suspected Ebola patients are “missing” after a health centre in the capital was looted.

The government had sought to reassure people, saying all the patients had been moved to another health facility.

But Information Minister Lewis Brown told the BBC that 17 inmates had gone “back into their communities”.

Nurses and doctors in some of the countries affected by Ebola in West Africa, are now not only fighting the outbreak, but also a deeply rooted mistrust by local communities.

The World Health Organisation says an estimated 1,145 people have died from the virus this year.

Focus on Africa’s Tomi Oladipo reports.

via BBC News – Ebola outbreak: Inside Liberias Monrovia treatment centre.

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Stimulating the part of the brain which controls movement may improve recovery after a stroke, research suggests.

Studies showed firing beams of light into the brains of mice led to the animals moving further and faster than those without the therapy.

The research, published in Proceedings of the National Academy of Science, could help explain how the brain recovers and lead to new treatments.

The Stroke Association said the findings were interesting.

Strokes can affect memory, movement and the ability to communicate.

Brain cells die when their supply of oxygen and sugars is cut off by a blood clot.

Stroke care is focused on rapid treatment to minimise the damage, but some recovery is possible in the following months as the brain rewires itself.

Stimulation

The team at Stanford University School of Medicine investigated whether brain stimulation aided recovery in animal experiments.

They used a technique called optogenetics to stimulate just the neurons in the motor cortex – the part of the brain responsible for voluntary movements – following a stroke.

After seven days of stimulation, mice were able to walk further down a rotating rod than mice which had not had brain stimulation. After 10 days they were also moving faster.

Brain

The researchers believe the stimulation is affecting how the wiring of the brain changes after a stroke.

They detected higher levels of chemicals linked to the formation of new connections between brain cells.

Lead researcher Prof Gary Steinberg said it was a struggle to give people drugs to protect brain cells in time as the “time window is very short”.

However he told the BBC that aiding recovery could be easier: “The advantage of treating during the recovery period is it’s longer, potentially it could be years, so it has huge potential.

“I predict that the kind of study we’re doing will help to push stimulation as a therapy for stroke and you can image how import that would be for the millions of stroke patients with disability.”

Light

Optogenetics uses an optic fibre to send light into the brain, which specifically activates cells that are genetically engineered to respond to the light.

It allows precision stimulation of parts of the brain in experiments.

The team at Stanford argue using optogenetics will allow them to uncover exactly what changes in the brain as it recovers from stroke,

Prof Steinberg said: “We’re also looking to see if optogenetically stimulating other brain regions after a stroke might be equally or more effective.

“The goal is to identify the precise circuits that would be most amenable to interventions in the human brain, post-stroke, so that we can take this approach into clinical trials.”

However, optogenetics cannot be used in people yet.

It would require genetic modification of the target cells, but Prof Steinberg argues “it may not be too far in the future that you’re doing refined and elegant stimulation” with optogenetics.

Dr Shamim Quadir, from the Stroke Association charity, said: “This is a very interesting study using light to stimulate specific brain cells of genetically altered mice in the early days after a stroke.

“Using this optogenetic technique could be helpful in improving our understanding of the mechanisms driving stroke recovery, however it is too early to tell exactly how this research might be developed for the treatment of human stroke patients.”

via BBC News – Brain stimulation helps in stroke.

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Public awareness campaigns are being stepped up in Liberia, where some people believe Ebola is a hoax

 

Seventeen suspected Ebola patients who went missing in Liberia after a health centre in the capital was attacked have been found, a minister has said.

“They were traced and finally they turned themselves in” at a treatment centre, Lewis Brown told the BBC.

The government had previously denied they were missing.

New UN figures show that 1,229 people have now died since the beginning of this year in the outbreak that has also hit Sierra Leone, Guinea and Nigeria.

Map: Ebola outbreak in West Africa

The World Health Organization (WHO) says there were 84 deaths reported between 14 and 16 August.

Doctors ‘improving’

Ebola has no known cure, but the WHO has ruled that untested drugs can be used to treat patients in light of the scale of the current outbreak – the deadliest to date.

It is transmitted by direct contact with the body fluids of an infected person. Initial flu-like symptoms can lead to external haemorrhaging from areas such as eyes and gums, and internal bleeding which can cause organ failure.

A man carries out a girl from an Ebola isolation centre as a mob overruns the facility in the West Point slum on August 16, 2014 in Monrovia, Liberia.
This man took a young girl out of the West Point health facility during the attack
Liberian Police dressed in riot gear deploy at a Doctors Without Borders Ebola treatment centre in Monrovia, Liberia (18 August 2014)
Security has been stepped up at health centres treating Ebola patients in Liberia

The Liberian information minister said the missing patients were now at the newly expanded treatment unit opened over the weekend at the John F Kennedy Memorial Medical Center in the capital, Monrovia.

Mr Brown also said the health of three Liberian doctors infected with Ebola had improved after they receiving the experimental drug Zmapp.

Two US missionaries, who were flown home for treatment from Liberia, are reportedly recovering from the virus after taking doses of the same medicine.

The drug was also given to a 75-year-old Spanish priest who contracted Ebola in Liberia, but he died in Spain last week.

In Nigeria, which has had four fatal Ebola cases, health officials say five people have now recovered from the virus and been discharged from hospital in Lagos. Another three are still being treated.

‘A hoax’

The attack on the quarantine centre, where 37 people were being held in Monrovia’s densely populated West Point township, took place on Saturday evening.

There are conflicting reports over what sparked the riot, in which medical supplies were also stolen.

line

Ebola Virus Disease (EVD)

A fruit bat is pictured in 2010 at the Amneville zoo in France.
Fruit bats are believed to be a major carrier of the Ebola virus but do not show symptoms
  • Symptoms include high fever, bleeding and central nervous system damage
  • Fatality rate can reach 90% – but current outbreak has about 55%
  • Incubation period is two to 21 days
  • There is no vaccine or cure
  • Supportive care such as rehydrating patients who have diarrhoea and vomiting can help recovery
  • Fruit bats, a delicacy for some West Africans, are considered to be virus’ natural host
line

Officials said the protesters were unhappy that patients were being taken there from other parts of the capital. Other reports suggested the protesters had believed Ebola was a hoax and wanted to force the centre to close.

The BBC’s Jonathan Paye-Layleh in Monrovia says there are also reports that the mattresses and linen being used by patients were taken during the attack.

The current outbreak is the deadliest since Ebola was discovered in 1976

In neighbouring Sierra Leone, the agricultural minister has said the outbreak is also having a severe impact on the economy, as 66% of people were farmers and agriculture accounted for 46% of GDP and 25% of all exports.

“We’re expecting devastating effects not only on the labour, but we’re also talking about farms being abandoned by people running away from the epicentres,” Joseph Sam Sesay told the BBC.

Since the outbreak spread to Nigeria in July, when a person infected with Ebola flew from Liberia to Lagos, several airlines have stopped flights to the worst-affected countries.

Kenya’s ban on people from Guinea, Liberia and Sierra Leone entering the East African nation comes into force on Wednesday – and Cameroon has closed its land, sea and air borders with Nigeria.

via BBC News – Ebola crisis: Liberia finds missing patients.

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